Irving I. Gottesman Emeritus Professor gotte003@umn.edu IRVING I. GOTTESMAN, Ph.D., Hon. FRCPsych (London) Drs. Irving & Dorothy BERNSTEIN PROFESSORSHIP in ADULT PSYCHIATRY SENIOR FELLOW in Department of Psychology UNIVERSITY OF MINNESOTA MEDICAL SCHOOL—TWIN CITIES SHERRELL J. ASTON PROFESSOR OF PSYCHOLOGY EMERITUS UNIVERSITY OF VIRGINIA, CHARLOTTESVILLE, VA

Statement of Interests

Irving Gottesman is known internationally for his work in the field of genetics. Gottesman, one of our most distinguished alumni, from the University of Virginia, received APA's Award for Distinguished Scientific Contribution in 2000. Gottesman was a member of our faculty from 1966-1980. His first extensive study of the genetics of schizophrenia used a twin register that had been around for 15 years. His findings confirmed that genes were undeniably a determining factor in schizophrenia. But, contrary to popular belief, he the “role played by family environment turned out to be less important than anyone would have guessed.” Gottesman found room for a wide range of non-genetic factors to consider.

Gottesman helped to establish in 1985 a clinical psychology training program at the University of Virginia. He has returned now to conduct research part-time for the Departments of Psychology and Psychiatry. Gottesman travels extensively consulting in the field of genetics.

Selected Publications

Fatemi, S.H., Laurence, J.A., Araghi-Niknam, M., Stary, J.M., Schulz, S.C., Lee, S., & Gottesman, I.I. (2004). Glial fibrillary acidic protein is reduced in cerebellum of subjects with major depression.  Schizophrenia Research, 69, 317-323.
 
Deshpande, S.N., Bhatia, T., Wood, J., Brar, J.S., Thelma, B.K., Ganguli, R., Day, R., Gottesman, I.I., & Nimgaonkar, V.L. (2004).  Evaluation of familial influences on the course and severity of schizophrenia among US and Indian cases.  Social Psychiatry and Psychiatric Epidemiology, 39, 369-374.

Gottesman, I.I. & Hanson, D.R. (2005).  Human development: biological and genetic processes.  Annual Review of Psychology, 56, 263-286.

Prescott, C.A., Caldwell, C.B., Carey, G., Vogler, G.P., Trumbetta, S.L., & Gottesman, I.I. (2005)  The Washington University twin study of alcoholism. American J. Medical Genetics (Neuropsychiatric Genetics) 134B, 48-55.

Subotnik, K.L., Asarnow, R.F., Nuechterlein, K.H., Fogelson, D.L., Thorpe, T.I., Payne, D.L., Giannini, C.A., Kuppinger, H.E., Torquato, R.D., Mintz, J., Hwang, S.S., & Gottesman, I.I.  (2005).  MMPI vulnerability indicators for schizophrenia and attention deficit disorder: UCLA family study of biological parents of offspring with childhood-onset schizophrenia or ADHD. Behavior Genetics, 35, 159-175.

Gottesman, I.I. & Erlenmeyer-Kimling, L. (2005).  Genetic enhancements in schizotypy theorizing. In M. Maj et al. (Ed.) Personality Disorders. [Vol. 8 WPA-Evidence and Experience in Psychiatry] London: Wiley Europe. Pp. 84-87..

Hasler, G., Drevets, W.C., Gould, T.D., Gottesman, I.I., & Manji, H.K. (2005). Toward constructing an endophenotype strategy for bipolar disorder. Biological Psychiatry.

Wong, A.H.C., Gottesman, I.I., & Petronis, A. (2005) Phenotypic differences in genetically identical organisms: the epigenetic perspective. Human Molecular Genetics, 14, 11-18.

Hanson, D.R. & Gottesman, I.I. (2005). Theories of schizophrenia: a genetic-inflammatory-vascular synthesis. BMC Medical Genetics 6:7.  http://www.biomedcentral.com/1471-2350/6/7 

Johnson, W. & Gottesman, I.I. (in press). Clarifying process vs. structure in human intelligence: stop talking about fluid and crystallized. Brain and Behavior Science.

Hanson, D.R. & Gottesman, I.I. (in press). Choreographing genetic, epigenetic, and stochastic steps in the dances of psychopathology.  Minnesota Symposia on Child Psychology Vol. x.

Maher, B.A. & Gottesman, I.I. (2005). Deconstructing, reconstructing, preserving Paul E. Meehl’s legacy of construct validity. Psychological Assessment, 17, 415-422.

Gould, T.D. & Gottesman, I.I. (2005).  Psychiatric endophenotypes and the development of valid animal models. Genes, Brain & Behavior.  http://www.blackwell-synergy.com/doi/full/10.1111/j.1601-183X.2005.00186.x

Carey, G. & Gottesman, I.I. (in press).  Genes and antisocial behavior: perceived versus real threats to jurisprudence. Journal of Law, Medicine & Ethics.

More at: http://www.people.Virginia.edu/~iig